Our research program focuses upon the application and development of new computational tools that target organic and enzymatic catalyst design, alternative environmentally friendly solvent design, and drug discovery. Fundamental problems in organic and medicinal chemistry are probed, such as elucidation of enzymatic reactions, controlling...
Research at the Agatemor Lab interfaces between chemistry and cell biology. Specifically, the lab develops chemistry-based tools to study and regulate biological systems. These tools include bioorthogonal chemical reporters, bespoke glycans and glycan ligands, redox-active biomaterials, and deep eutectic solvents. The overarching goal is to use...
Leonidas G. Bachas joined the University of Miami as dean of the College of Arts and Sciences in July 2010. A distinguished analytical and biological chemist, Bachas was formerly the Frank J. Derbyshire Professor of Chemistry at the University of Kentucky and chair of its Department of Chemistry. Bachas’s tenure at Kentucky was marked...
Research Interests: Metal Cluster Chemistry, Organometallic Synthesis, Catalysis, X-ray Crystallography.
We are interested in designing and exploring the chemistry of transition metal complexes containing sterically encumbered ligands derived from main group elements. The transition metals of interest are those belonging to...
Catalysis Thermochemistry Metal Complexes Sulfur Chemistry Kinetic Studies Spectroscopy
The goal of our research is to understand what controls reactions important to catalysis of reactions like nitrogen fixation. Binding and activation of dinitrogen, nitriles, hydrogen, carbenes, and sulfur to metal complexes are all...
Research in the Knecht Group focuses on the use of biological macromolecules to construct nanomaterials for specifically targeted applications. These applications include catalysis, self-assembly, detection, and materials design. We use a wide variety of biological, chemical, and material synthetic strategies to design and engineer specific...
Brief description of research
Our research group aims at understanding the surface chemistry, spectroscopic and microscopic investigation of organic and biological supramolecular complexes. The chemistry of monolayers of supramolecular complexes is of paramount importance on account of many potential applications in diverse fields such as...
One of the most exciting topics in modern chemistry is the possibility of creating nano-devices such as molecular computers. Already there are molecules which can operate as transistors, resistors, diodes, motors and molecular switches which may be activated by temperature, pressure or electro-magnetic radiation. Tying these devices together...
Research in the Meier lab takes place at the interface of physical and biological chemistries and utilizes a range of spectroscopic and computational techniques as well as novel synchrotron-based Mössbauer methods to elucidate metal involvement in the proliferation of diseased states. More specifically, my research program focuses on...
While nature has mastered the art of engineering non-equilibrium structures that enable energy capture, conversion, and storage with unrivaled efficiency, this level of structural control over synthetic materials with dimensions spanning the nano- to mesoscale remains elusive. Consequently, current technology exploits equilibrium-based...
Computational chemistry is a fast emerging field and today is widely applied to solve complex chemical and biochemical problems in both academia and the chemical and pharmaceutical industries. In this field, highly accurate quantum chemical methods implemented in the advanced commercial software and state-of-the-art computers including...
Life sustaining highly specific chemical reactions occur in the confined and organized medium of protein. Our projects aimed at achieving similar selectivity in (photo)chemical reactions explore the use of readily available hosts that bear similarity to biological media. In our laboratory, spatially confined cavities provided by crystals,...
My current research program combines chemical synthesis, spectroscopic analysis and fluorescence microscopy with the ultimate goal of developing chemical probes for imaging and sensing applications.
For over sixty years, nuclear magnetic resonance (NMR) continues to be an active and fertile area of scientific research, with applications ranging from magnetic resonance imaging (MRI) to testing fundamental theories and applications of quantum mechanics. However, one of the main challenges in NMR over its history has been in increasing...
Research in my group is in the general areas of bioorganic and materials chemistry with a specific focus on the development of fluorescent analogs of biomolecules. We design, synthesize and characterize probes targeting specific biomacromolecular structures including DNA, transmembrane proteins, enzymes and receptors. This effort incorporates...
The ultimate goal of our studies is to gain a deeper understanding of the molecular basis for important human diseases such as sudden death, myocardial infarction, rotavirus infection and HIV infection that cause substantial mortality and suffering. The structural details revealed by our work may provide clues for the design of more effective...
Our research interests lie broadly in organic chemistry, polymer chemistry, materials chemistry, chemical biology, drug delivery, and nanomedicine, with emphasis on the translation of polymer chemistry to functional nanomaterials designed for advanced disease treatment. The central theme of will involve the fundamental development of synthetic...
Teaching and Mentoring
Hynes teaches undergraduate courses on atmospheric science, atmospheric and environmental chemistry and also “Molecules of Life”. This class is team taught with Professor Mike Gaines from the Department of Biology and it explores the modern science of biological molecules, which occurs at the...